OPTIMIZATION OF CARDIOPULMONARY BYPASS PRIME FLUID TO PRESERVE MICROCIRCULATORY PERFUSION DURING ON-PUMP CORONARY ARTERY BYPASS GRAFT SURGERY: PRIME STUDY PROTOCOL FOR A DOUBLE-BLIND RANDOMIZED TRIAL

Abstract Background Acute microcirculatory perfusion disturbances and organ edema are important factors leading to organ dysfunction during cardiac surgery with cardiopulmonary bypass (CPB).Priming of the CPB system with crystalloid or colloid fluids, which inevitably leads to hemodilution, could contribute to this effect.However, there is yet no o

The Search and Rescue optimization algorithm (SAR) is a recent metaheuristic inspired by the exploration’s behaviour for humans throughout search and rescue processes.The SAR is applied to solve the Combined Emission and Economic Dispatch (CEED) and Economic Load Dispatch (ELD).The comparative performance of SAR against several metaheuristic

Since the first reported case in December of 2019, the coronavirus disease 2019 (COVID-19) has became an international public health emergency.So far, there are more than 228,206,384 confirmed cases including 4,687,066 deaths.Kidney with high expression of angiotensin-converting enzyme 2 (ACE2) is one of the extrapulmonary target organs affected in

Mediastinal masses occur in dogs and cats and are often investigated with cytology.However, discrimination between the two most common lesions (thymoma and lymphoma) may be challenging, especially when small/medium lymphocytes represent the prevalent population.The aim of the present study is to describe the flow cytometric aspects of mediastinal m